Zika Virus: An Update

Aedes mosquito-01The Zika virus was first isolated from a Rhesus Macaque monkey in 1947 in the Zika Forest in Uganda (zika meaning “overgrown” in the Luganda language–gotta love useless trivia!); it was first isolated from a human in 1954 in Nigeria. It appeared sporadically along the equator in Africa and Asia for several decades until it spread to French Polynesia in 2013 and then to Latin America, Mexico, the Caribbean, and now the US.

Illness from Zika was rare until the pandemic began in 2007. The illness it caused was mild and self-limited until October 2015, when we began to see babies with microcephaly (very small brains) born to mothers who had been infected while pregnant. Evidence shows that these babies may also have eye abnormalities that will  effect their vision. There have been links to serious deformities in the joints in the arms and legs of affected babies. A report published August 30, 2016 noted that 6% of the babies affected by Zika also have hearing loss. According to the AAP as of November 4, 2016, their are five main birth defects: severe microcephaly with partially collapsed skull, decreased brain tissue with subcortical calcifications, extreme muscle tone, eye damage with macular scarring and increased pigment, and limited joint motion range.

There have now been more than 1500 cases of microcephaly in Brazil; in the most severe areas the incidence has been as high as 1:100 births.  On August 15, 2016 a state of emergency was declared in Puerto Rico, where they now have 10,690 confirmed Zika cases, including 1,035 pregnant women. Currently, more than 500 pregnant women in the US have shown evidence of a possible Zika infection.

Symptoms

Zika is a flavivirus related to Dengue, Chikungunya, and West Nile encephalitis. It is transmitted by several species of Aedes mosquitos which can, after biting an infected human, infect another person. Transmission has also been reported through blood transfusions and sexual contact.

The newly infected person may not have any symptoms at all, or may develop symptoms of illness within 2 weeks: fever, a bumpy red rash, sore joints, and pink eye. Less common symptoms include aching muscles, headache, and vomiting. The illness itself is usually mild and self limited.

Treatment

There is no preventative vaccine available yet and no treatment, other than pushing fluids, resting, and treating the symptoms with acetaminophen (Tylenol). The ill person should not take aspirin, ibuprofen (Motrin, Advil), or naproxen (Aleve) until Dengue fever is ruled out, to avoid the risk of bleeding.

Where is it?

As of now, local transmission has been reported in more than 0 countries and territories. Current recommendations are that women who are pregnant, especially in their first trimester, do not travel to any of these areas. If they have to travel, they should do what they can to protect themselves from mosquito bites: wear long pants and long sleeved shirts, preferably treated with permethrin insect repellant; sleep in air conditioned rooms, screened in areas or with permethrin treated mosquito nets; and wear insect repellant, because these mosquitos are active during the daytime.

If you do travel to these areas and develop the symptoms of Zika after returning home, pregnant or not, see your doctor. Avoid mosquitos for the first few days, so that you will not be the source of spreading infection.

Men who have had Zika should use barriers during sex for at least 6 months after the infection; women for 8 weeks. Use of a barrier is recommended for at least 8 weeks after travel to endemic areas even if you have no symptoms.

As of today, we have had 1962 confirmed cases of the infection in the US, with 413 in Florida. Twenty eight of those were caught from local mosquitos. We have the Aedes mosquito along our southern coast and in southern California.

Prevention

In all likelihood the same measures we used to contain Denque in the US will contain Zika, but its spread is still possible. Taking precautions is certainly sensible.

  • Get rid of standing, stagnant water.
  • Clean up piles of garbage, because mosquitos love to breed in trash.
  • Put up or repair your window screens.
  • Spray.

Another possibility to limit spread of the infection is releasing GMO mosquitos with a lethal gene, to decrease the population of the bugs. When this was done in the Caman Islands the mosquito population decreased by 80%.

If you are pregnant, stay out of the endemic areas when possible. Take sensible precautions: clean up standing water and trash, put up or repair window screens, and wear insect repellant.

And keep an eye out for current recommendations from public health officials, because the places and numbers change daily.

DomesticatedMomster
The Blogger's Pit Stop

8 Easy Ways to Prevent Childhood Cancer

Cute girl of school age in superhero costume

More than 9000 kids get cancer in the US every year (about 1 in 450). The most common are leukemias, lymphomas, and brain tumors, but there are many different kinds. If you would like up to date numbers, the  AAP has them here.

Cancer is a group of more than 100 diseases caused by the cells in a person’s body multiplying out of control. Cancer is separated into different types depending on what sort of cell it originated from (blood, brain, lung…) and if it invaded nearby body parts (a tumor) or spread to other organs (metastasis). That might be a smidge simplified, but you get the idea.

Your children’s genes, the DNA they inherit from you, influence their risk of cancer–not something you can change. But lifestyle and environment also influence their risk, and there you can have an impact.

That impact includes not only your kid’s exposures in childhood, but also the example they see in your behavior and the habits you establish that will carry forward into their adult lives. What you teach them in childhood can protect them throughout their lives.

What to do to lower your child’s risk of getting cancer:

  1. First, the obvious one: don’t use tobacco, and don’t allow anyone else to smoke around your kids. I know, easier said than done, but an estimated four out of five cancers are caused by tobacco. The poisons in tobacco damage DNA, increasing the incidence of 14 different cancers including lung, some leukemias, voice box, throat, liver, kidney… Secondhand smoke alone increases cancer risk by 25%. The sidestream smoke off the burning end of a cigarette has 3 times the carbon monoxide, 10 times the nitrosamines and hundreds of times the ammonia of exhaled smoke. Add to this that if you smoke, your child’s chances of becoming a daily addicted smoker increase by 25 times, boosting their risk even more. Just don’t. No excuse is good enough.
  2. Also well known: protect them from sunburns to prevent skin cancer. Use at least SPF15 and reapply through the day. Seek shade during peak hours. Stick a hat on their head that shades their face, and a pair of sunglasses on their nose.
  3. Feed them a healthy diet with lots of fiber, fruits and vegetables. Avoid processed meats and an overabundance of red meat and salt. A healthy diet helps your body remove harmful chemicals, prevent and repair damage to DNA, and block the formation of cancer causing chemicals. A less healthy diet has been linked to breast, mouth, esophagus and GI cancers.
  4. Encourage exercise. Exercise stabilizes levels of hormones like estrogen and insulin that have been linked to cancer. An active lifestyle decreases the incidence of breast, bowel, and uterine cancers.
  5. Keep them at a healthy body weight. Fatty tissue produces hormones that influence the way cells grow. Cell overgrowth is at the root of cancers. Obesity has been linked to breast cancer, esophageal and bowel cancers, and liver, kidney, pancreas and uterine cancers.
  6. Limit their exposure to chemicals. Indoor pesticides have recently been shown to  increase children’s risk of leukemia by 47%. Be aware of the chemicals you might be exposed to at your job, wear appropriate safety gear, and don’t bring poisons home on your clothes–cancer causing chemicals such as arsenic, benzene, and asbestos are still used in industry. Check the use instructions (do they need to be used in a well ventilated area?) and ingredients in the products you do use at home. You can check for harmful ingredients in household products at nih.gov. Store household chemicals such as cleaners, paints, degreasers, and strippers safely high up and locked away.
  7. In the “be a good example” category: limit your alcohol consumption. Alcohol increases the amount of cancer causing chemicals in your body, and affects hormone levels. It also amplifies the toxic effects of tobacco. Drinking alcohol increases your risk of breast, mouth, throat and bowel cancers.
  8. Avoid certain kinds of infections. Infection can increase cancer risk by causing chronic inflammation and suppressing the immune system. Hep B increases your kid’s risk, so get them the vaccine, and teach them to avoid iv drugs and indiscriminate sex. Be careful with tattoos: Hep C also increases risk, and 41% of it comes from tattoos. Helicobactor pylori  increases cancer risk–doctors look for it with reflux disease, gastritis and ulcers.  Human Papillomavirus  works by causing cells to divide rapidly (hence the appearance of a wart). We lose 4000 women to preventable cervical cancer yearly, and the incidence of oral cancers due to HPV is increasing dramatically. The CDC recently announced that the vaccine has decreased the incidence of HPV in teens by 2/3. Get your child the HPV vaccine when he or she hits 11 or 12.

Cancer risk factors seem to hit the hardest when a baby is still in the womb, and in adolescence when their bodies are rapidly growing and changing, so these are the times when a parent can absolutely have an effect in preventing cancer.

A healthy lifestyle stacks the deck in your child’s favor, dramatically decreasing their odds of getting cancer. Protect them from cancer causing sunburns and poisons, get those vaccines, establish good habits, and be a good example. There is no down side to a healthy diet, regular exercise, and limiting their exposure to toxins, and it may increase their chances of hanging around for a while.

Domesticated Momster

Pesticides: Not a Major Food Group

bleach boy-01A recent statement from the American Academy of Pediatrics suggested that we should limit our children’s exposure to pesticides.

It turns out that chemicals designed to kill insects and rodents are not good for children. Who knew?

In large doses, pesticides cause acute poisonings, with symptoms including dizziness, nausea, headaches, twitching or weakness. Smaller doses over a longer time can harm your child’s brain or hormonal systems. When pesticides injure a child’s brain they can cause developmental delays, and attention and behavior problems. Hormonal effects can impact your child’s growth and perhaps his or her reproductive ability. We do need to limit our children’s exposure!

Children are more vulnerable to poisons than adults, not less. Their bodies are actively growing and maturing and are thus easier to damage, like a gymnast caught mid leap. They have faster metabolisms: their hearts beat more quickly and their lungs breathe more rapidly, allowing chemicals in more quickly and in larger amounts. Also, their protective systems aren’t mature and don’t work as well as those of adults to stop the damage.

So, how do we lower children’s exposure in our day-to-day lives? The most common place for your child to ingest pesticides is in the food that they eat, particularly the fruits and vegetables. This does not mean they can skip their veggies! Just wash them first, eat a variety of different produce (different vegies have different amounts of pesticides), and buy organic when you can. Your local farm stand is, of course, your best friend.

Children are also exposed to pesticides in their homes and yards, so we may need to make some changes there. Keep all of your household pest products in their original containers with child proof caps intact. Just today I had a child drink a degreaser because her mom had stored it in a soda bottle! Store poisons out of reach and out of sight in a locked cupboard. If you are using a pesticide and the phone rings, close the container and put it out of reach while you are out of visual range. I have seen more than a few kids poisoned when mom went to see why the baby was crying, or to answer the door. Kids are quick.

Read and follow the directions on the container. Use pesticides only when there is a problem, never to just prevent one. Less is always better. When you do use them, use crevice and crack treatments, not bombs. Think about how your kids live on the surfaces to which you are applying the treatment: kids lie on the ground, crawl under things, and touch stuff and put their hands in their mouths. Don’t put the rat poison behind the couch – your 2 year old will find it. My amazing, brilliant grandchild found the mouse poison behind the dishwasher. World’s worst grandma.

Change your clothes after you use pesticides, and store your shoes outside.

If you have a wooden play structure that was built between 1970 and 2004 and not made of cedar or redwood, the wood was probably treated with chromated copper arsenate. Arsenic also is not good for children, so you may want to replace the structure.

Read the ingredients on lawn and garden products and any pet products. Organophosphates (most commonly malathion, but there are dozens) were banned from home use in 2001, but many people have old products sitting around, or use commercial products at home. They are also still used in public parks and schools.

In America we use more than 1 billion pounds of pesticides every year in our farms, homes and public spaces. Ask what is used by your city and at your child’s school. There are many newer, safer products that have been developed in the last few years, so suggest alternatives and avoid the organophosphates when you can.

Stay safe and be healthy!